IVF

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AFFORDABLE IVF STARTING FROM £2,550.

IVF

AFFORDABLE EXCELLENCE: EXPERIENCE CUTTING-EDGE IVF CARE IN PRAGUE

IVF treatment in the Czech Republic is more affordable compared to the UK or USA, thanks to lower medical staff costs. Prague clinics offer cutting-edge and top-quality care at a global standard.

That's why over 10,000 individuals from the United Kingdom and the USA choose to utilize these services every year.

Experience the excellence of Czech premium care. We guarantee your satisfaction as well.

IVF

For whom is it intended?

1. If you and your partner have been on an unsuccessful conception journey for more than six months or a year (depending on your age), IVF could be the answer you've been seeking.

2. If you're facing challenges related to the quality of your eggs or sperm, IVF offers a promising solution to help overcome these obstacles.

3. For couples experiencing infertility due to immunological causes, IVF presents a ray of hope, providing a way forward on your quest to conceive.

4. If you're a woman with blocked fallopian tubes or endometriosis, IVF emerges as a transformative option, empowering you to transcend these limitations.

Let IVF be the catalyst that propels you towards the family of your dreams. Our compassionate experts are ready to guide you every step of the way, offering personalized care and support throughout your IVF journey. Together, let's turn possibilities into cherished realities. 

84% CUMULATIVE SUCCESS RATE

HOW IVF ABROAD WORKS

CONTACT US

ONLINE CONSULTATION
YOUR QUESTIONS ANSWERED

TREATMENT PLAN
PREPARED BY A DOCTOR

PREPARATION AT HOME
5-10 DAYS

TRIP TO PRAGUE, CZECH REPUBLIC.
WE WILL BOOK YOUR HOTEL,
ARRANGE AIRPORT TRANSFERS
AND GUIDE YOU 24/7

FIRST VISIT OF THE CLINIC
BOTH PARTNERS: 2 DAYS

SECOND VISIT OF THE CLINIC
(SEVENTH DAY OF THE CYCLE)
ONLY WOMAN: 8 - 12 DAYS

RETURNING HOME

ZERO WAITING

FREE SKYPE CONSULTATION: DISCOVER YOUR TREATMENT OPTIONS NOW

Unlock your treatment possibilities with our exclusive offer: a complimentary Skype consultation awaits you! Prepare for your journey and explore the multitude of options available to you. Take advantage of this limited-time opportunity to connect with our dedicated medical patient coordinator, who will guide you every step of the way. What's the next exciting chapter? Simply reach out to us through our convenient contact form, and let's embark on this life-changing adventure together.

EXTRAORDINARY APPROACH TAILORED TO WOMEN UP TO 49

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10 REASONS WHY CHOOSE US

1. 84% CUMULATIVE SUCCESS RATE

Experience our unwavering commitment to delivering exceptional results year after year. Our egg donation program boasts an impressive cumulative success rate of over 84%, signifying the attainment of pregnancy following a single egg collection and one or more successful embryo transfers within a single therapy. Trust in our expertise as we pave the way to your dreams becoming a reality.

2. 24/7 SUPPORT: YOUR JOURNEY MADE STRESS-FREE 

We recognize the potential stress and challenges that come with undergoing therapy abroad. That's why we provide you with a dedicated personal treatment coordinator right from the beginning of your treatment process. Need assistance? Reach out to your coordinator via call or email, and expect a prompt response. We're available Monday to Friday, with occasional Saturday availability as well. For urgent cases outside of working hours, rest assured that our on-call doctor is just a phone call away. Your well-being is our top priority, ensuring peace of mind every step of the way.

3. ZERO WAITING

Begin Your Journey Instantly! At our clinic, we prioritize your time and eliminate the hassle of waiting. Experience the convenience of a remarkably short waiting period for your initial consultation, with no waiting list for treatment, including therapy with egg donation. You can start your journey right away, as it solely depends on your menstrual cycle. Furthermore, for patients undergoing IVF with egg donation, we ensure seamless synchronization of cycles with the donor, a process typically taking just a few weeks. Embrace the freedom to embark on your path to parenthood without unnecessary delays.

4. DISCOVER A WORLD OF POSSIBILITIES: 700+ HEALTHY DONORS AWAIT! 

Elevate your journey with the remarkable option of egg donation, an avenue of artificial fertilization utilizing eggs graciously donated by anonymous individuals. This solution proves especially beneficial for women facing challenges with ovarian functionality or their own eggs' fertilization potential. It's also a transformative path for those seeking to minimize the risk of genetic birth defects. With a vast database of over 700 healthy donors, our expert consultants meticulously select the ideal match based on a comprehensive questionnaire completed by you and your partner. Together, we strive to maximize compatibility in terms of phenotypic parameters, ensuring a harmonious union. Unleash the potential of finding the perfect donor and unlock the door to your dreams of parenthood.

5. YOUR PERSONAL GUIDE: MEET YOUR TREATMENT COORDINATOR 

Experience personalized support from fluent English-speaking treatment coordinators who will accompany you throughout your journey. From your initial contact, they are here to answer your questions, provide pre-consultations, and ensure a seamless experience. With their expertise and care, you can confidently navigate the process. Discover the peace of mind that comes with having a dedicated treatment coordinator by your side.are our priority, and our dedicated treatment coordinators are here to make your journey seamless and stress-free.

6. DISCOVER THE CONVENIENCE: PRAGUE, JUST A FLIGHT AWAY

Conveniently located in central Europe, Prague awaits your arrival with ease. Hop on a plane and reach us from a multitude of major airports, including London Stansted, London Luton, London Gatwick, Bristol, Leeds, Liverpool, Manchester, Newcastle, Birmingham, Edinburgh, Glasgow, and Dublin. With flight durations of approximately 2 to 2.5 hours, your journey to our doorstep will be swift and seamless. Embrace the accessibility and embark on a transformative experience in the heart of Prague.

7. TRANSPARENT PRICING: NO HIDDEN COSTS, GUARANTEED 

With our all-inclusive packages, there are no additional expenses to worry about. Our prices (excluding medication) listed in the price list cover everything you need for your IVF treatment. From egg collection and ICSI fertilization to extended cultivation, assisted hatching, embryo transfer, and even vitrification with one-year storage for remaining embryos – we've got you covered. Rest easy knowing that your journey is mapped out with complete transparency and no surprises along the way.

8. EMBRACE CUTTING-EDGE ADVANCEMENTS: UNLEASHING THE POWER OF STATE-OF-THE-ART TECHNOLOGY 

At our clinic, we stay at the forefront of the industry, constantly tracking the latest trends and procedures to enhance the success of our IVF program. We are committed to investing in advanced devices and technologies, harnessing their potential to propel the effectiveness of our treatments. Experience the transformative power of state-of-the-art technology as we strive to provide you with the highest level of care and maximize your chances of achieving your dreams of parenthood.

9. DISCOVER PRAGUE: YOUR UNFORGETTABLE 7-DAY EXPERIENCE 

Unleash the magic of Prague as you embark on a 7-day journey unlike any other. With the ideal duration for your treatment, you'll also have ample time to explore the city's captivating sights. Immerse yourself in the rich history and vibrant culture, creating cherished memories along the way. Prague awaits, ready to offer you an unforgettable experience that goes beyond expectations.

10. AFFORDABLE IVF STARTING FROM €2,400! 

Experience the incredible value of IVF in the Czech Republic, where costs are significantly lower compared to the UK or USA. Our competitive prices are made possible by reduced medical staff expenses, ensuring accessible fertility solutions without compromising on quality. Take a glimpse at our comprehensive price list and discover the possibilities that await you on your journey to parenthood.

UNLOCK YOUR PREGNANCY POTENTIAL
Get in touch with us today!

FREQUENTLY ASKED QUESTIONS

What is the age limit for IVF?
Do you offer IVF to single women and same sex couples too?
How is male infertility diagnosed?
When is it appropriate to undergo IVF?
Do I need a referral from my doctor for my first visit to the clinic?
What is endometriosis and how many women are affected?
What are the causes of male infertility?
What are the causes of female infertility?
What are polycystic ovaries?
Why are IVF cycles sometimes unsuccessful?
When should I take a pregnancy test after IVF?
What regimen do I have to follow after embryo transfer?
What is the success rate of IVF after the age of 40?
What is the difference between IVF and ICSI?
What is IVF?
What are the risks associated with IVF?
It is advisable to perform PGD/PGS before IVF?
Is it possible to undergo IVF without fallopian tubes or ovaries?
Is it possible to reduce the risk of genetic deseases?
How to increase the success of IVF?
How long before I can repeat IVF?
How does age affect fertility?
How do I know which day is the first day of the cycle?
Can IVF be done without hormonal stimulation?
What conditions do I have to meet for IVF?
Do you offer IVF to single women and same sex couples too?
Can you determine the gender of a child before IVF?

What is the age limit for IVF?

Experience the transformative power of IVF, available to individuals up to the age of 49. We understand the significance of time in your fertility journey, and we encourage you not to delay treatment. Age plays a crucial role in the success of IVF, making it all the more important to take proactive steps towards parenthood. Discover the possibilities that lie within reach and embark on your path to parenthood with us. Let us help you make your dreams a reality, regardless of age.

Do you offer IVF to single women and same sex couples too?

At our clinic, we are dedicated to providing personalized fertility solutions that adhere to valid Czech legislation. As per the current regulations, IVF treatment is available to heterosexual couples, allowing for a wide range of relationship dynamics, including married and unmarried couples. While we are unable to offer IVF treatment to single women and same-sex couples due to legal constraints, we remain committed to supporting and guiding you in exploring alternative pathways to parenthood. Our compassionate team is here to provide guidance, resources, and information to help you navigate your unique fertility journey. Together, let's explore the possibilities and find the best path to realizing your dreams of starting or expanding your family.

How is male infertility diagnosed?

Male infertility is typically diagnosed through a comprehensive evaluation that includes a semen analysis, also known as a spermiogram. This test assesses the quantity and quality of sperm present in the ejaculate. The results of the semen analysis are considered normal if the ejaculate meets the following criteria:

1) Sperm count: At least 15 million sperm per milliliter of semen.
2) Sperm motility: At least 40% of the sperm exhibit forward movement or motility.
3) Semen volume: The total volume of the ejaculate is at least 1.5 milliliters.

These parameters serve as general guidelines for evaluating male fertility. However, it's important to note that additional factors, such as sperm morphology (shape), vitality, and other aspects, may also be assessed to provide a comprehensive analysis of male fertility health. It is advisable to consult with a medical professional for a thorough evaluation and interpretation of the results. 

When is it appropriate to undergo IVF?

If you and your partner have been actively trying to conceive through regular, unprotected intercourse for a year without success, it is appropriate to consider visiting an IVF clinic. At our clinic, we will conduct a thorough examination to identify the underlying cause of infertility. In some cases, we may discover that the cause of the problem can be effectively treated without the need for IVF.

By assessing your specific situation and conducting the necessary tests, we can determine the most appropriate course of action to increase your chances of achieving pregnancy. Our goal is to provide personalized care and explore all available options to help you start or expand your family. It is important to consult with our experienced medical professionals to receive individualized guidance based on your unique circumstances. 

Do I need a referral from my doctor for my first visit to the clinic?

You do not need a referral from your doctor to schedule your first visit to our clinic. Our doors are open to all individuals and couples seeking consultation regarding fertility treatment. If you have previously undergone any examinations or treatments related to your fertility, we encourage you to bring along the results or relevant documentation.

We particularly recommend a visit to our assisted reproduction center for couples who have been actively trying to conceive for a minimum of one year without success. Our team of experts will carefully evaluate your situation, discuss your medical history, and conduct necessary tests to determine the most suitable treatment options for you. Rest assured, we are here to provide the support and guidance you need on your journey towards parenthood. 

What is endometriosis and how many women are affected?

Endometriosis is a prevalent gynecological condition that affects a significant number of women in their reproductive years. It is estimated that up to 10% of women worldwide are affected by this condition.

Endometriosis is characterized by the presence of endometrial tissue outside the uterus. Normally, the endometrium is the lining of the uterus that thickens and sheds during the menstrual cycle. However, in endometriosis, these endometrial cells are found in other areas, such as the ovaries, fallopian tubes, and pelvic cavity.

During the menstrual cycle, these misplaced endometrial cells also respond to hormonal changes, causing them to shed and bleed. However, as there is no way for the blood to exit the body, it can lead to inflammation, pain, and the formation of scar tissue or adhesions.

Women with endometriosis often experience symptoms such as more intense menstrual pain (dysmenorrhea), chronic pelvic pain, pain during sexual intercourse, and in some cases, blood in the urine or bowel movements.

Furthermore, endometriosis is a well-known cause of female infertility. The presence of endometrial tissue in areas outside the uterus can affect fertility by causing hormonal imbalances, interfering with the normal functioning of the reproductive organs, and contributing to inflammation and scarring.

If you suspect you may have endometriosis or are experiencing any related symptoms, it is important to consult with a medical professional for diagnosis and appropriate management. Treatment options can help alleviate symptoms, improve fertility, and support your overall reproductive health. 

What are the causes of male infertility?

Male infertility can be attributed to various factors, which can have a negative impact on fertility health. Some common causes of male infertility include:

1. Lifestyle Factors: Certain lifestyle choices can contribute to reduced fertility in men. These factors may include smoking tobacco, marijuana use, excessive alcohol consumption, increased genital temperature (from tight clothing, hot baths, saunas, laptop use on the lap), and high levels of stress.

2. Pre-Testicular Causes: These causes involve insufficient development of the male gonads (testicles). It can be due to hormonal imbalances, genetic conditions, or certain medical conditions affecting the production of hormones necessary for sperm production.

3. Testicular Causes: Testicular causes are related to issues with the testicles themselves, resulting in poor-quality ejaculate with low sperm count or no sperm at all. Testicular causes can be associated with genetic disorders, hormonal imbalances, testicular injury, or conditions that affect sperm production.

4. Post-Testicular Causes: Post-testicular causes involve conditions that affect the transport or passage of sperm after production. This can include blockages or obstructions in the vas deferens (the tubes that carry sperm), prostatitis (inflammation of the prostate gland), or ejaculatory duct obstruction.

To diagnose male infertility, a key test is a semen analysis (spermiogram). This test evaluates the quantity and quality of sperm in the ejaculate. Based on the results of the semen analysis, further examinations and potential treatments for male infertility can be planned.
It is essential to consult with a healthcare professional specializing in fertility to determine the underlying causes of male infertility and develop an appropriate treatment plan tailored to individual circumstances. 

What are the causes of female infertility?

Female infertility can arise from various factors, including both lifestyle and medical causes. Some common causes of female infertility include:

1. Age: A woman's fertility declines with age, particularly after the age of 35, as the quality and quantity of eggs decrease.

2. Lifestyle Factors: Certain lifestyle choices can negatively impact female fertility. These include high levels of stress, inadequate sleep, smoking, and excessive alcohol consumption.

3. Ovarian Factor: Ovarian dysfunction can occur due to hormonal imbalances, polycystic ovary syndrome (PCOS), premature ovarian failure, or other conditions affecting the normal functioning of the ovaries.

4. Tubal Factor: Blocked or damaged fallopian tubes can prevent the sperm from reaching the egg or hinder the fertilized egg from traveling to the uterus for implantation. This can result from pelvic infections, endometriosis, or previous surgeries.

5. Endometriosis: Endometriosis is a condition in which the tissue that normally lines the uterus (endometrium) grows outside the uterine cavity. It can cause inflammation, scarring, and damage to the reproductive organs, leading to fertility issues.

6. Immunological Factors: In some cases, the body may produce antibodies that target sperm, eggs, or embryos, interfering with fertilization and implantation.

7. Genetic Causes: Certain genetic abnormalities can impact fertility. In some instances, fertility may not be compromised, but there may be an increased risk of conceiving a child with a congenital defect. In vitro fertilization (IVF) can be employed to minimize this risk through preimplantation genetic testing.

It is crucial to consult with a healthcare professional specializing in fertility to determine the underlying causes of female infertility. A comprehensive evaluation will help identify the specific factors contributing to infertility and guide the development of an appropriate treatment plan tailored to individual needs. 

What are polycystic ovaries?

Polycystic ovaries, also known as polycystic ovarian morphology (PCO), refer to a condition in which the ovaries contain numerous small cysts or follicles. These cysts are not harmful or cancerous but are fluid-filled sacs that surround the eggs.

Polycystic ovary syndrome (PCOS) is a common hormonal disorder that can cause polycystic ovaries. It is estimated to affect up to 10% of women and often manifests in women under the age of 30. PCOS is characterized by a combination of symptoms, including:

1. Irregular or Absent Menstrual Cycles: Women with PCOS may experience irregular menstrual periods or may not have periods at all due to hormonal imbalances.

2. Excessive Hair Growth (Hirsutism): Increased hair growth on the face, chest, back, or other areas of the body, often in a male pattern, can occur in women with PCOS.

3. Thinning Hair: PCOS can lead to thinning hair or hair loss, typically in a pattern similar to male-pattern baldness.

4. Weight Gain or Difficulty Losing Weight: Many women with PCOS struggle with weight management or experience weight gain, often due to insulin resistance and hormonal imbalances.

Polycystic ovary syndrome is a complex condition that affects the hormonal balance in the body, leading to irregular ovulation and difficulties with fertility. In PCOS, eggs are often not released from the ovaries during the menstrual cycle, resulting in their accumulation within the ovaries. As a result, these eggs are unable to be fertilized by sperm, leading to challenges in achieving pregnancy.

It is important for women experiencing symptoms of PCOS or struggling with infertility to consult with a healthcare professional specializing in reproductive health. Proper diagnosis and management of PCOS can help regulate menstrual cycles, improve fertility, and address associated symptoms and concerns. 

Why are IVF cycles sometimes unsuccessful?

The success of an IVF cycle can be influenced by various factors, and it is not always possible to pinpoint the exact reasons why a particular cycle may be unsuccessful. However, some common factors that can contribute to unsuccessful IVF cycles include:

1. Egg Quality: The quality of the eggs retrieved during IVF plays a crucial role in the success of fertilization and embryo development. As women age, the quality of their eggs tends to decline, which can impact the chances of successful implantation and pregnancy.

2. Sperm Quality: The quality of sperm used for fertilization is equally important. Poor sperm quality, including low sperm count, reduced motility, or abnormal morphology, can affect the fertilization process and reduce the likelihood of successful embryo development.

3. Embryo Development: The development of embryos in the laboratory is another critical factor. Not all fertilized embryos progress normally, and some may fail to reach the required developmental stages for successful implantation.

4. Implantation Issues: Even if high-quality embryos are transferred, the implantation process is complex and can be influenced by factors such as the receptivity of the uterine lining, the embryo's ability to attach and develop, and immune responses within the body.

5. Underlying Health Conditions: Certain underlying health conditions in either partner, such as hormonal imbalances, uterine abnormalities, or genetic factors, can impact the success of IVF.

6. Lifestyle Factors: Lifestyle choices, including smoking, excessive alcohol consumption, and poor diet, can negatively affect fertility and the outcome of IVF cycles.

It is important to remember that each individual and IVF cycle is unique, and the reasons for unsuccessful cycles can vary. However, with careful evaluation and personalized treatment planning, subsequent IVF cycles can be optimized to increase the chances of successful pregnancy. Your healthcare provider or fertility specialist can guide you through the process and help determine the most appropriate strategies for future attempts. 

When should I take a pregnancy test after IVF?

After undergoing an IVF cycle, the timing of a pregnancy test is crucial for obtaining accurate results. While individual clinics may have slight variations in their recommendations, a general guideline is as follows:

1. Waiting Period: It is essential to allow sufficient time for the embryo to implant in the uterus following the embryo transfer. Typically, a urine pregnancy test should not be taken before the 12th day after the transfer. Testing earlier may yield false-negative results as the pregnancy hormone (hCG) may not have reached detectable levels yet.

2. Confirmatory Testing: If the initial pregnancy test at the 12th day is negative, it is recommended to repeat the test on the 14th and 20th day after the embryo transfer. This allows for further observation of hCG levels and provides more accurate results. However, some clinics may suggest specific testing intervals, so it's best to follow the guidelines provided by your healthcare provider.

3. Positive Test: If the pregnancy test shows a positive result, it is important to schedule an ultrasound to confirm the location of the pregnancy and rule out the possibility of an ectopic pregnancy. This is typically done around 6-7 weeks of gestation.

It is crucial to adhere to the recommended testing schedule and follow the instructions provided by your fertility clinic or healthcare provider. They will be able to guide you regarding the appropriate timing and frequency of pregnancy testing to ensure accurate results and provide appropriate care throughout your IVF journey. 

What regimen do I have to follow after embryo transfer?

After embryo transfer, it is generally advised to follow certain guidelines to optimize the chances of successful implantation and pregnancy. While specific recommendations may vary depending on the clinic and individual circumstances, here are some common guidelines to consider:

1. Rest and Relaxation: It is advisable to avoid strenuous physical activities and heavy lifting for a certain period after the embryo transfer. Resting and taking it easy during this time may help reduce the risk of any potential complications and allow the embryo to implant securely.

2. Stress Management: Minimizing stress levels is important as high levels of stress may potentially impact the success of the embryo implantation. Engaging in relaxation techniques such as deep breathing, meditation, or gentle exercises like yoga may help in managing stress.

3. Medication Regimen: It is crucial to strictly follow the prescribed medication regimen as instructed by your healthcare provider. This may include hormonal medications such as progesterone supplements to support the uterine lining and maintain a favorable environment for embryo implantation.

4. Healthy Lifestyle: Maintaining a healthy lifestyle is always beneficial. It is recommended to consume a balanced diet, stay hydrated, avoid excessive caffeine and alcohol, and refrain from smoking. These lifestyle factors can contribute to overall well-being and promote a favorable environment for embryo development.

5. Regular Activities: There is generally no need to take sick leave from work after embryo transfer unless your occupation involves physically demanding tasks or poses a risk to your health or the success of the treatment. However, it is advisable to discuss your work situation with your healthcare provider to ensure appropriate guidance based on your individual circumstances.

It is essential to consult with your fertility specialist or healthcare provider for specific post-embryo transfer instructions tailored to your situation. They can provide personalized recommendations and address any concerns you may have throughout the process. 

What is the success rate of IVF after the age of 40?

The success rate of IVF after the age of 40 is generally lower compared to younger age groups. Advanced maternal age can impact the quality and quantity of eggs, leading to decreased fertility and lower chances of successful pregnancy. However, each individual's situation is unique, and success rates can vary based on various factors such as overall health, reproductive history, and specific circumstances.

While using donor eggs is a recommended option for women over the age of 40, it is important to consult with a fertility specialist who can provide personalized advice based on your specific situation. Donor eggs can offer higher success rates as they come from younger and healthier individuals. By using donor eggs, the age-related decline in egg quality and quantity can be overcome, increasing the chances of successful IVF.

It is crucial to start IVF treatment as early as possible, as even a few months' delay can have an impact on the success rate. The fertility clinic's doctors can also recommend suitable laboratory methods and techniques to enhance the chances of successful treatment. These may include procedures such as preimplantation genetic testing (PGT) to select the healthiest embryos for transfer, or advanced culture systems to optimize embryo development.

It is important to have realistic expectations and discuss the success rates and potential challenges associated with IVF at an older age with your fertility specialist. They can provide detailed information, guidance, and support to help you make informed decisions about your fertility journey. 

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What is the difference between IVF and ICSI?

IVF (In Vitro Fertilization) and ICSI (Intracytoplasmic Sperm Injection) are both techniques used in assisted reproduction, but they differ in the way fertilization is achieved. Here's a breakdown of the differences between IVF and ICSI:

1. IVF: In IVF, the process involves stimulating the woman's ovaries to produce multiple mature eggs. These eggs are then retrieved and combined with sperm in a laboratory dish or a culture medium. The sperm and eggs are left to fertilize naturally, with the sperm penetrating the egg to initiate fertilization. Once fertilization occurs, the resulting embryos are cultured in the laboratory for a few days before one or more embryos are transferred into the woman's uterus.

2. ICSI: ICSI is a more specialized form of IVF. In ICSI, a single sperm is directly injected into an individual egg using a microneedle or a pipette. This precise and targeted method of fertilization bypasses any barriers that may prevent natural fertilization from occurring, such as poor sperm quality or sperm-egg interaction issues. ICSI is typically recommended when there are male fertility factors like low sperm count, poor motility, or abnormal morphology. It allows for successful fertilization even with very few or low-quality sperm.

In summary, the main difference between IVF and ICSI lies in the fertilization process. In IVF, fertilization occurs when sperm and eggs are combined in a dish or culture medium, relying on natural fertilization. In ICSI, a single sperm is injected directly into an egg, ensuring fertilization even in cases with compromised sperm quality or quantity.

The choice between IVF and ICSI depends on various factors, including the specific fertility issues faced by the couple. Your fertility specialist will assess your situation and recommend the most suitable treatment approach to maximize the chances of successful conception and pregnancy. 

What is IVF?

IVF (In Vitro Fertilization) is an assisted reproductive technology that helps individuals or couples who are experiencing fertility issues to achieve pregnancy. The process involves several steps:

1. Ovarian Stimulation: The woman's ovaries are stimulated using hormonal medications to produce multiple mature eggs instead of the usual one egg that is naturally released during each menstrual cycle. This is done to increase the chances of obtaining viable eggs for fertilization.

2. Egg Retrieval: Once the eggs have matured, they are retrieved from the woman's ovaries using a minor surgical procedure called follicular aspiration. This procedure is usually performed under sedation or anesthesia to minimize discomfort.

3. Sperm Collection: On the day of egg retrieval, the male partner or sperm donor provides a semen sample. The sperm is then prepared in the laboratory to isolate the most motile and healthy sperm for fertilization.

4. Fertilization: In the laboratory, the retrieved eggs and the prepared sperm are combined together. Fertilization can occur through the natural method (allowing sperm to penetrate the eggs) or through the use of ICSI (Intracytoplasmic Sperm Injection) where a single sperm is injected directly into each egg.

5. Embryo Development: After fertilization, the embryos are cultured in a controlled laboratory environment for several days. The development and quality of the embryos are monitored by the embryologists.

6. Embryo Transfer: The selected embryos, usually one or more, are transferred into the woman's uterus through a thin catheter. This procedure is typically performed on an outpatient basis and does not require anesthesia.

7. Pregnancy Test: About two weeks after the embryo transfer, a pregnancy test is performed to determine if the procedure was successful. If the test is positive, further monitoring will be done to assess the progress of the pregnancy.

It's important to note that IVF can be performed using the intended parents' own eggs and sperm, as well as donated eggs or sperm, depending on the specific circumstances and fertility challenges. The process is tailored to each individual or couple's needs and is conducted under the supervision of a fertility specialist.

IVF has provided hope and helped many individuals and couples achieve their dream of having a child, especially in cases where other fertility treatments have been unsuccessful. 

What are the risks associated with IVF?

While IVF is generally a safe procedure, it does carry certain risks and potential complications. Here are some of the risks associated with IVF:

1. Ovarian Hyperstimulation Syndrome (OHSS): This is a rare but potentially serious complication of ovarian stimulation. It occurs when the ovaries become overstimulated and produce too many eggs. Symptoms of OHSS may include abdominal pain, bloating, nausea, vomiting, and shortness of breath. Most cases of OHSS are mild, but severe cases can require medical intervention and close monitoring.

2. Multiple Pregnancy: IVF increases the chances of multiple pregnancies, such as twins or triplets. Multiple pregnancies are associated with higher risks for both the mother and the babies, including preterm birth, low birth weight, and other complications. Many clinics take measures to reduce the risk of multiple pregnancies by limiting the number of embryos transferred.

3. Ectopic Pregnancy: In some cases, the embryo may implant outside the uterus, typically in the fallopian tube. This is known as an ectopic pregnancy and can be a life-threatening condition. Early detection and treatment are essential to prevent complications.

4. Miscarriage: The risk of miscarriage with IVF is similar to that of natural conception. Factors such as maternal age, embryo quality, and underlying medical conditions can influence the risk of miscarriage.
5. Birth Defects: While the risk of birth defects in children conceived through IVF is generally low, it may be slightly higher compared to natural conception. However, advancements in embryo screening techniques (such as preimplantation genetic testing) can help reduce this risk.

6. Emotional and Psychological Impact: IVF treatment can be emotionally and psychologically challenging for individuals and couples. The stress, anxiety, and disappointment associated with the process can take a toll on mental well-being. Seeking support from healthcare professionals, support groups, or counseling services can be helpful in managing these challenges.

It's important to remember that the risks and outcomes of IVF can vary depending on individual circumstances and underlying factors. Your fertility specialist will discuss these risks with you and provide personalized guidance and recommendations to minimize potential complications. 

It is advisable to perform PGD/PGS before IVF?

Performing Preimplantation Genetic Testing (PGT), which includes both Preimplantation Genetic Diagnosis (PGD) and Preimplantation Genetic Screening (PGS), can be advisable in certain situations before undergoing IVF. Here are some scenarios where PGT may be recommended:

1. Genetic Diseases: If one or both parents carry a known genetic disorder, PGT can be performed to screen embryos for the specific genetic mutation or chromosomal abnormality. This helps in selecting embryos without the genetic disease for transfer, reducing the risk of passing on the condition to the offspring.

2. Recurrent Miscarriages: When a woman has experienced multiple miscarriages, PGT can be beneficial. It allows for the selection of embryos with a normal chromosomal profile, improving the chances of a successful pregnancy and reducing the risk of miscarriage due to chromosomal abnormalities.

3. Advanced Maternal Age: As a woman's age increases, the risk of chromosomal abnormalities in embryos also rises. PGT can help identify chromosomally normal embryos, increasing the likelihood of a successful pregnancy and reducing the risk of miscarriage or certain genetic disorders associated with advanced maternal age.

4. Family Balancing: In cases where parents desire a specific gender of the child for family balancing purposes, PGT can be used to identify embryos of the desired gender for transfer.

It's important to note that PGT is not a substitute for prenatal screening or diagnostic tests performed during pregnancy to detect congenital anomalies. PGT focuses on screening embryos before transfer to identify specific genetic conditions or chromosomal abnormalities. Prenatal screening and diagnostic tests are still recommended during pregnancy to assess the health and development of the fetus.

The decision to undergo PGT should be made in consultation with a fertility specialist or genetic counselor who can assess your specific circumstances, provide personalized recommendations, and discuss the potential benefits, limitations, and ethical considerations of PGT. 

Is it possible to undergo IVF without fallopian tubes or ovaries?

Yes, it is possible to undergo IVF without fallopian tubes or ovaries, but the approach may differ depending on the specific situation:

1. Without Fallopian Tubes: If a woman does not have fallopian tubes or her fallopian tubes are blocked, IVF is an ideal solution. In IVF, the fertilization process occurs outside the body, bypassing the need for fallopian tubes. The eggs are retrieved from the ovaries, fertilized with sperm in a laboratory, and the resulting embryos are then transferred directly into the uterus.

2. Without Ovaries: If a woman does not have functioning ovaries or has undergone surgical removal of the ovaries, she will not be able to produce her own eggs for IVF. In such cases, the woman can still undergo IVF treatment using donated eggs. Donated eggs from a compatible donor are fertilized with sperm in the laboratory, and the resulting embryos are transferred to the recipient's uterus.

In both scenarios, the woman can still carry a pregnancy and experience the joys of motherhood, even if she does not have fallopian tubes or functioning ovaries. It is important to consult with a fertility specialist who can evaluate your specific situation, provide personalized guidance, and discuss the available options for IVF treatment, including the use of donated eggs if necessary. 

Is it possible to reduce the risk of genetic deseases?

Yes, preimplantation genetic testing (PGT) can help reduce the risk of genetic diseases in offspring. PGT involves the analysis of embryos created through IVF to identify genetic abnormalities or specific genetic diseases before they are transferred to the uterus.
There are two main types of PGT:

1. PGT-A (Preimplantation Genetic Testing for Aneuploidy): This type of testing screens for chromosomal abnormalities, such as aneuploidy (abnormal number of chromosomes). PGT-A is commonly used to increase the chances of a successful pregnancy by selecting embryos with a higher likelihood of implantation and a reduced risk of miscarriage.

2. PGT-M (Preimplantation Genetic Testing for Monogenic Disorders): PGT-M is used to detect specific genetic disorders that are known to be present in the family. By analyzing the embryos for these specific genetic mutations or abnormalities, only unaffected embryos or embryos with a low risk of inheriting the disorder are selected for transfer.

PGT is performed by taking one or a few cells from the embryo, usually at the blastocyst stage (around 5-7 days after fertilization). The cells are then analyzed using various genetic testing techniques, such as PCR (polymerase chain reaction) or next-generation sequencing, to identify any abnormalities or specific genetic conditions.

It's important to note that PGT cannot guarantee the birth of a healthy baby, as it does not test for all possible genetic conditions and there is a possibility of false negatives or false positives. However, it can significantly reduce the risk of certain genetic diseases and provide couples with more information to make informed decisions about their family planning.

If you have concerns about genetic diseases or disorders, it is recommended to consult with a fertility specialist or a genetic counselor who can provide further guidance and information about the suitability and availability of PGT for your specific situation. 

How to increase the success of IVF?

To increase the success of IVF treatment, various additional laboratory methods and techniques can be employed. Here are a few examples:

1. ICSI (Intracytoplasmic Sperm Injection): ICSI involves the direct injection of a single sperm into the egg, which can be particularly beneficial in cases of male infertility or if previous fertilization attempts have been unsuccessful.

2. EmbryoGlue: EmbryoGlue is a specialized medium that helps facilitate the implantation of embryos into the uterine lining. It provides an optimal environment for embryo development and can increase the chances of successful implantation.

3. Assisted Hatching: Assisted hatching involves creating a small opening in the outer shell (zona pellucida) of the embryo before transfer. This technique can assist the embryo in hatching out of its shell and increase the likelihood of successful implantation.

4. Fertile Plus: Fertile Plus is a culture medium that provides optimal conditions for embryo development. It contains essential nutrients and growth factors that support embryo growth and viability.

In addition to these laboratory methods, there are several other factors that can contribute to the success of IVF:

1. Preimplantation Genetic Testing (PGT): PGT can help identify chromosomally normal embryos, reducing the chances of implanting embryos with genetic abnormalities and increasing the likelihood of a successful pregnancy.

2. Optimizing ovarian stimulation: Individualized ovarian stimulation protocols can be tailored to a woman's specific needs, taking into account factors such as age, ovarian reserve, and response to previous treatments. This helps to optimize the number and quality of retrieved eggs.

3. Embryo selection: The use of morphological assessment or time-lapse imaging systems can aid in the selection of the most viable embryos for transfer.

4. Preparing the uterus: Preparing the uterine lining through hormonal supplementation, endometrial scratching, or other techniques can create a more receptive environment for embryo implantation.

5. Lifestyle factors: Adopting a healthy lifestyle by maintaining a balanced diet, engaging in regular exercise, managing stress levels, and avoiding harmful habits such as smoking and excessive alcohol consumption can positively impact the success of IVF.

It's important to note that the success of IVF can vary depending on individual circumstances, such as age, overall health, and underlying fertility issues. Consulting with a fertility specialist is crucial to determine the most appropriate strategies and techniques to maximize the chances of a successful IVF outcome based on your specific situation. 

How long before I can repeat IVF?

The recommended interval between IVF cycles can vary depending on individual circumstances and the specific treatment protocol. While it's important to consult with your fertility specialist for personalized advice, here are some general guidelines:

1. Stimulated IVF cycles: In a stimulated IVF cycle, where hormonal medications are used to stimulate the ovaries and produce multiple eggs, it is common to have a waiting period between cycles. This allows the body to recover from the previous treatment and for the menstrual cycle to return to its normal pattern. Typically, a break of 2 to 3 months is recommended to allow for optimal ovarian function and response to subsequent stimulation.

2. Frozen embryo transfer (FET) cycles: In cases where embryos have been cryopreserved (frozen) during a previous IVF cycle for later transfer, the interval between FET cycles is generally shorter. Depending on the specific circumstances and individual factors, FET cycles can often be scheduled within the next menstrual cycle or within a few weeks.

It's important to note that these are general recommendations, and the timing between IVF cycles may be adjusted based on various factors, including the woman's age, overall health, previous treatment outcomes, and individualized treatment plans. Your fertility specialist will assess your specific situation and provide guidance on the most appropriate timing for repeating IVF. They will consider factors such as ovarian reserve, response to previous treatments, and any necessary adjustments to optimize your chances of success.

Remember to discuss your concerns and expectations with your fertility specialist, as they will be able to provide you with personalized advice tailored to your unique circumstances and help you make informed decisions about the timing of your next IVF cycle.

How does age affect fertility?

Age plays a significant role in a woman's fertility. Here's how age affects fertility:

1. Quantity and quality of eggs: Women are born with a finite number of eggs, and this supply gradually diminishes over time. As a woman ages, her ovarian reserve, which refers to the quantity of remaining eggs, decreases. Additionally, the quality of eggs tends to decline with age. Older eggs have a higher risk of chromosomal abnormalities, which can result in infertility, miscarriage, or genetic disorders.

2. Ovulation and hormonal changes: As women age, hormonal changes occur that can affect ovulation. Irregular menstrual cycles or a decline in regular ovulation can make it more difficult to conceive.

3. Increased risk of medical conditions: With advancing age, women have a higher likelihood of developing certain medical conditions that can impact fertility. Conditions such as endometriosis, fibroids, or polycystic ovary syndrome (PCOS) can affect fertility and increase the risk of infertility.

4. Decreased response to fertility treatments: Older women may have a reduced response to fertility treatments, including IVF. The ovaries may not respond as well to hormonal stimulation, leading to fewer eggs retrieved during the IVF cycle.

It's important to note that while age is a significant factor in female fertility, it is not the sole determining factor. Fertility varies among individuals, and some women may have more favorable reproductive health at an older age. However, it is generally recommended that women who are planning to conceive should be aware of the potential impact of age on their fertility and consider seeking medical advice if they are experiencing difficulties.

In cases where age-related decline in egg quality and quantity becomes a significant factor, using donated eggs from a younger woman can be an effective option to overcome infertility challenges and increase the chances of successful conception.

It's always recommended to consult with a fertility specialist who can assess your individual situation, provide personalized guidance, and discuss appropriate fertility treatment options based on your age and specific fertility profile. 

How do I know which day is the first day of the cycle?

To determine the first day of your menstrual cycle, you need to identify the day when your period begins. Here's how you can determine the first day of your cycle:

1. Start counting from the first day of full menstrual flow: The first day of your menstrual cycle is considered to be the first day of full menstrual flow, which is characterized by bright red blood. Spotting or light flow before this day is not considered the start of your cycle.

2. Ignore spotting or light flow: It's common for some women to experience light spotting or discharge before their period starts. It's important to distinguish between this premenstrual spotting and the actual start of your period. Only count the first day when you have a full flow of menstrual blood.

3. Consider the time of day: If you start experiencing menstrual flow before midnight (before 12:00 am), that day is considered the first day of your cycle. However, if your flow starts after midnight (after 12:00 am), you would count the following day as the first day of your cycle.

For example, if you start bleeding anytime between midnight and 11:59 pm on a specific day, that day is considered the first day of your cycle. If you start bleeding after 12:00 am, you would count the next day as the first day of your cycle.

It can be helpful to track your menstrual cycles on a calendar or using a smartphone app to have a better understanding of your cycle length and to predict the timing of future cycles. This can be particularly useful when planning fertility treatments or trying to conceive.

If you are unsure about determining the first day of your cycle or if your periods are irregular, it's recommended to consult with your healthcare provider or a gynecologist who can provide personalized guidance and help you track your menstrual cycles accurately. 

Can IVF be done without hormonal stimulation?

Yes, IVF can be performed without hormonal stimulation, known as a natural cycle IVF. In a natural cycle IVF, instead of using hormonal medications to stimulate the ovaries and produce multiple eggs, only one naturally matured egg is retrieved.

A natural cycle IVF may be recommended for certain individuals, such as those who are at higher risk of complications from hormonal stimulation or those who prefer a more minimalistic approach to treatment. However, it's important to note that the success rates of natural cycle IVF are generally lower compared to stimulated IVF cycles. This is because the chances of obtaining multiple eggs and embryos for selection and transfer are significantly reduced.

The decision to pursue natural cycle IVF should be made in consultation with a fertility specialist who can evaluate your specific circumstances and determine the most suitable treatment approach for you. They will consider factors such as your age, ovarian reserve, and reproductive history to help you make an informed decision about the best course of action for your individual situation. 

What conditions do I have to meet for IVF?

To undergo IVF treatment, there are certain conditions that need to be met. Here are the typical requirements:

1. Age: Generally, women up to the age of 49 are eligible for IVF treatment.

2. Medical Evaluation: Before starting IVF, both the woman and her male partner will undergo a comprehensive medical evaluation. This includes a thorough assessment of their reproductive health, hormone levels, and any underlying medical conditions that may affect fertility.

3. Relationship Status: IVF treatment is typically provided to couples who are in a committed relationship. The woman must apply for IVF treatment together with her male partner. This requirement ensures that both partners are involved in the decision-making process and the subsequent stages of the treatment.

It's crucial to consult with a fertility specialist or reproductive endocrinologist who can assess your individual circumstances and provide guidance on the specific conditions and requirements for IVF treatment in your particular location. They will be able to guide you through the entire process, explain any legal considerations, and help you understand the eligibility criteria that need to be met. 

Do you offer IVF to single women and same sex couples too?

In accordance with the current legislation in the Czech Republic, IVF treatment is exclusively provided to heterosexual couples. Therefore, IVF services are not currently extended to single women or same-sex couples. The application process for IVF treatment requires the signature of both a man and a woman, irrespective of their marital status.

Do I have to be married to my partner if we want to undergo IVF?

Marriage is not a requirement for undergoing IVF treatment. However, both partners (a woman and a man) are required to provide written consent as a statutory condition for the treatment. This consent is necessary for both the use of the couple's own reproductive cells and for treatments involving donated cells.

Can you determine the gender of a child before IVF?

Under current legislation, gender selection for non-medical reasons is generally not permitted. However, in certain cases where one of the parents carries a serious genetic disorder that is specifically linked to one gender, gender determination may be allowed for medical reasons. It is important to consult with your healthcare provider or fertility clinic to understand the specific regulations and options available in your country or region.

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